How about some more flaws for Pathfinder?
Chemical Dependence-Flaw-you need something or things go bad in a hurry-Choose one of two levels for this flaw-Minor or Major-Minor is equivalent to one feat, while Major is equivalent to two. You must consume the object of your dependence once every 24 hours for minor or twice every 24 hours for major. If you fail to do so, you take a -2 on all check for minor, and a -4 for major. When presented with an opportunity to use the object of your dependence you must make a will save-DC 10+1/2 level for minor and DC 15 15+1/2 level for major. Your dependence may be used against you to force your character to things they would normality not do.
Thoughts?
Throat Punch Games 
Reminds me of something they did back in 3.5 Ed. I wouldn’t be opposed to bringing Flaws back; they were an interesting concept.